Standardization of protein biomarker measurements: Is it feasible?

Standardization of protein biomarker measurements: is it feasible?

The standardisation of measurements of protein biomarkers, which are potentially heterogeneous in terms of fragmentation, modification, substitution, primary, secondary, tertiary and quaternary structure, is a demanding task. However, they are a prime target for standardisation efforts due to the importance of protein biomarkers in diagnostics and health care and the typically observed signific...

Is It Feasible or Desirable?

During the past decade, advances in device technology (eg, drug-eluting stents), development of safer anticoagulants (eg, bivalirudin), and refinement in procedural techniques have led to a dramatic improvement in the effectiveness and safety of percutaneous coronary intervention (PCI), despite increasing clinical and anatomic complexity of treated patients.1 As safety and effectiveness have be...

HIV Eradication: Is it Feasible?

Provable Security: How Feasible Is It?

Strong, machine-checked security proofs of operating systems have been in the too hard basket long enough. They will still be too hard for large mainstream operating systems, but even for systems designed from the ground up for security they have been counted as infeasible. There are high-level formal models, nice security properties, ways of architecting and engineering secure systems, but no ...

Ambulatory anorectal surgery--is it feasible locally?

Currently, anorectal procedures are done in an inpatient setting in most local hospitals. This study examines the feasibility of performing these procedures in an outpatient setting. Patients (age range 16 to 65 years) with anorectal complaints requiring surgery were randomized into 2 groups of 40 patients each. Procedures performed included haemorrhoidectomy, fistulotomy, lateral sphincterecto...